PILL FATIGUE? HATE NEEDLES? TRY THIS INSTEAD

Welcome To Melt Supplement Strips

SPEAKER_03 0:19

Thanks for coming on. And why don't you just introduce yourself and what we got going on?

SPEAKER_01 0:24

Yeah. So my name is Sam. I'm one of the co-founders of Melt Supplement Strips, and we've created the new way to supplement with dissolving strips that melt in your mouth in under 60 seconds. So no pills, no powders, no injections. Just one strip on the tongue, and that's it.

SPEAKER_02 0:38

Have you tried MELT? Yeah. I know you mentioned. Yeah, I've tried pretty much most of their stuff. All the colors. Sam brought a bunch of them. Yeah. Yeah. So no, it's you know, like do being on supplements for so long, you know, you sometimes get tired of taking so many pills and stuff. Yeah. And this just makes it an easier way to um take it. So what led you guys to like go with these strips and and what did you start with? Like, because you didn't start with a whole line, but you must have started with something that kept going.

SPEAKER_01 1:16

So when I was younger, I did take growth hormone injections for around five years, and I've never liked needles. Um, my dad would inject me every single night and it burned, it bruised. We'd go on trips, it was super inconvenient. And so every single night throughout those five years, I asked myself, why is there not a different way, a needle-free way, to deliver these compounds? And so that question had been it had been lingering in my mind since I was probably 12. And then in junior high, I developed POTS, the uh autonomic nervous system disorder. And that then led to powders and pills and all the supplement challenges of everything being slow, inefficient, and a hassle to take. And throughout that process, I'm like, okay, it's really time to go create the new delivery format. We need something better. I need something better. And it actually started out as an electrolyte strip, funny enough. Um, at that time, sodium was a really, really important part of my recovery, but we realized that we couldn't fit enough electrolytes

Needles And POTS Spark The Idea

SPEAKER_01 2:10

into a strip. And so I brought on some of the top PhDs and the top scientists in the space to help develop the formulas that are now MELTS today.

SPEAKER_03 2:17

Okay. So why were you on growth hormone? And what age did you start at?

SPEAKER_01 2:22

So I started around 12. I was originally supposed to be 5'3, so uh my NBA dreams never came true. A little taller now, but um now I'm around 5'7, so definitely did its job. And yeah, so from 12 to then uh I think it was like my sophomore year of high school is when I stopped.

SPEAKER_00 2:38

Okay.

SPEAKER_01 2:39

And then uh the pills and powders and all the supplement challenges that started also, I guess, around I was 12 to 7th grade is when I developed POTS. And then high school is when that got pretty bad. And then I spent a lot of time in the Mayo Clinic where I got the supplement recommendations, but realized it was all really, really difficult to actually benefit from.

SPEAKER_03 2:56

Okay. And what's your educational background? Yeah, great question.

SPEAKER_01 2:59

Sound like a pharmacist or so I was at um ASU for my first two years of undergrad, studying data analysis. Funny enough, I wish I would have studied biochem. It would have saved me a lot of time and money. Um, but I was there for two years. I was working on the company the entire time. Probably should have spent a little more time on classes, but was in the early stages of building the company, making art or doing RD in my dorm room.

SPEAKER_04 3:22

Yeah.

SPEAKER_01 3:23

And uh two years in, ASU became our first investor. So we won what's called the new venture challenge. Um, a group of serial entrepreneurs come together, and so you pitch to get into the class. I think there were 11 of us. It's a nine-week competition, and by the end of the nine weeks, there's about half the class left. You pitch and we place first. And so after that, I realized I've got two options startup or school. Which one do I want to do? Startup one. And so I dropped out academically, whatever you want to call it. Um, and I've been full-time with a company since then. So it's been around three years now.

SPEAKER_02 3:56

Because AI would have taken over your other major.

SPEAKER_01 3:59

Exactly. Yeah, I know.

SPEAKER_03 4:00

I'm using codex for data analysis now. Yeah, true that. So you start a melts. What do you guys offer?

SPEAKER_01 4:09

Yeah, great question. So we have a pretty comprehensive supplement line. Here you see our glutathione strips is the retin, NAD plus is the yellow one, our nootropic for focus energy, and mental clarity is the blue one, and then our deep sleep strips are the purple. We also have a multivitamin, vitamin D and K. Um, and then we have what's called our proline, which has various aminos in there as well.

SPEAKER_03 4:28

What's in the purple?

SPEAKER_01 4:30

So the sleep strips are incredible. They have uh low-dose melatonin, apogenin, valerian root, magnolia bark.

SPEAKER_02 4:37

Um Do you have ashwagana in there?

SPEAKER_01 4:39

No ashwagana, but we do have L-thenine and gas. Yeah, right. Yeah, okay.

SPEAKER_02 4:44

It it does put you put you to sleep. It's really good at getting yeah, deep sleep with that stuff.

SPEAKER_01 4:50

Uh, one of my favorite stories from the sleep strips, we were at a pop-up uh a couple months ago, and there was a local Pilates instructor that told me she was not able to sleep through the night. She's waking up like 3 a.m. and I go, Carly, you have to try these sleep strips. She was wearing a whoop and her score or it was either a whoop and aura ring. Her sleep score is like in the 50s and 70s, and it would not improve. First night taking those into the 90s. Wow. So you what's really nice about those is they help you fall asleep faster, stay asleep.

SPEAKER_02 5:16

Um, you don't get the grogginess, like the melatonin grogginess because it's very low dose.

SPEAKER_01 5:22

100%. The melatonin gummies, they use five to ten milligrams, which is just it's way too much. Like, yep, it can be helpful for your let's say you're taking a flight to Europe for a summer trip or something. Um, it can be helpful as a circadian rhythm reset, but daily it's too much. Your body then relies on that, you wake up groggy, and so this is meant to promote really quality deep sleep on a daily basis.

SPEAKER_03 5:43

Yeah, because that that's not as deep into it as he is, but I've just found out like even five milligrams of melatonin is it's kind of too much because it shuts down your body from creating it naturally and at the times you need it, like when you actually need your body to make it while you're in sleep, it's kind of shut down.

SPEAKER_02 6:07

So it has magnesium in it too, right? So that one doesn't. I thought I thought I saw, or no? No, so you know it best. You tell them, Ruse. Yeah, but like apogenin and L-thenine are gonna be excellent for you know getting getting to sleep. And that's why that's pretty much big in the like compound industry because L-thenin' is gonna lower your cortisol levels and uh your fight or flight flight response. So, and that's what people are putting into their coffee to get rid of the jitters

Dropping Out To Build The Company

SPEAKER_02 6:40

so they can drink more caffeine without the jitters. So, yeah, in the morning you drink coffee to get up. But if you're trying to go go to sleep at night or need a late afternoon coffee, add L thean into it and I just have a coffee to wake up and then have a coffee to go to sleep. Well, some people need that, you know, like need to work till later, like eight, ten o'clock, whatever, at night. I I've gone away from it, but if you need to um get that extra cup of coffee, L thean and can help you like kind of relax and get to sleep.

SPEAKER_01 7:15

Yeah, and we actually have it in the brain fuel strips too. We pair it with perixanthine, which is the cleat and metabolite of caffeine. So you get the energy boost without the crash, which the L-theanine, it's it's actually studied. Um, there's a big study on L-theene and caffeine together. And in a a two-to-one dose is typically the sweet spot for that.

SPEAKER_02 7:33

Yeah, and perixanthine, that's like I I don't know, I've tried the capsules for it because it's supposed to make you more productive than caffeine without, and actually, like I think there's studies with like long-term focus and memory. I think it was improved for a longer amount of time than caffeine is on its own. So perxanthine was like, I don't know, it's probably quality-wise. I I think I took quality stuff, but I didn't feel like I did with caffeine as focused as I did with caffeine. I don't know crystal meth. And have you thought about crystal meth strips?

SPEAKER_00 8:15

Those ones up and coming. No, I'm just kidding.

SPEAKER_02 8:18

But uh apigenin's the other one. What is apigenin byproduct of?

SPEAKER_01 8:23

That's is it so a lot of the compounds in the sleep strips are naturally derived from uh different botanicals, yeah. And so apigenin works with GABA um because what happens with GABA can have a really hard uh a really difficult time crossing the blood-brain barrier. Yeah, and so apigenin allows our body to use that better and to use what we already have in there more. Um and so what you find is more of that mental quieting, more of that relaxation that allows you to actually fall asleep.

SPEAKER_03 8:49

So, what in it helps you stay asleep?

SPEAKER_01 8:51

Good question. So, valerian root is gonna be one of the things there. Um, melatonin is an interesting ingredient where a lot of people don't fully understand melatonin. Melatonin is a it's like a sleep timer for our bodies, and it can definitely age sleep onset. Um, but things like apogen and things like L-the and things like valerian root are gonna help us stay asleep throughout the night.

SPEAKER_03 9:12

Okay, because uh some people have trouble falling asleep, some people have trouble with like waking up, so it sounds like it's uh very well thought out to like just fall asleep, maintain that sleep status, and wake up without that, like my my wife's taken everything and it it either helps her fall asleep or stay asleep, and either one she's done, but like she's just groggy the whole next day. So she's like, it's not even worth it. I'd rather just get shitty sleep and like just make it through the day.

SPEAKER_02 9:51

So what what's interesting the thing with apogena I was trying to get

Sleep Strips And Daily Deep Rest

SPEAKER_02 9:55

like that's what I found out. Oh, it's like from chamomile. That's what they it's like an extract from chamomile that gets you that uh relaxed state. So a lot of the things in this are to lower your cortisol level so you are able to stay asleep, and that's that's where your cortisol starts going up, and that's where you're gonna wake up in the middle of the night. Um also you go to the bathroom, you wake up because of that cortisol spike you're diurasing yourself. 100%.

SPEAKER_01 10:28

Well, especially if you have to drink chamomile tea, it's got more liquid in your body, and it's more reason for a 3 p.m. wake up or it's a strip, he's pop on your tongue and you're good to go.

SPEAKER_02 10:35

The other thing, like I I know when you take injectable glutathione, sure, you're not supposed, you know, you're taking it separately from like the IV, like anything else, IV. So when you're doing the strips, have you found any, you know, like if you're like in the mornings, uh when I got the samples, I took two or three different strips, but I would take the glutathione pretty much last versus like you know, the vitamin A and D and some of the other stuff. Yeah, do you see any interactions with when you're putting them under strips?

SPEAKER_01 11:11

Good question. With the glutathione, what I typically do is I'll take that before I eat in the morning.

SPEAKER_02 11:15

Yeah.

SPEAKER_01 11:15

So I either do that first thing in the morning or before I go to bed.

SPEAKER_02 11:18

Yeah.

SPEAKER_01 11:18

And so that way um you're able to get more of the detox benefits, and then you don't have to worry about interactions or food uh fighting against the supplements that you're taking. Yeah. Whereas with something like vitamin D, right, you definitely want the healthy fats for the absorption.

SPEAKER_02 11:29

So, how did you test like how effective these are as compared to taking oral supplements?

SPEAKER_01 11:35

Yeah, great question. So we ran a PK study on the glutathione strips, and that showed up to 94% bioavailability, which is really, really um it was an amazing breakthrough because there's a lot of doubt amongst oral supplements, right? People they take so many pills and they spend hundreds of dollars and they go, I don't feel anything. Is it actually working? Exactly. Yeah. I mean, like L-theanine orally, around 50% bioavailability, NAD, 10 to 20%, glutathione, 1%. Yeah. We're with these, because they're able to deliver the the supplements and the compounds to your to the cells into the areas where they're actually needed much more uh effectively without having to take the long route through the gut and then eventually where they need to go. Um, that allows them to be much more effective and not basically have expensive urine.

SPEAKER_03 12:19

Yeah, so um just breaking it down for people who don't get it, like a lot of these you you can inject even IV, right? Um that's like direct blood source, putting it in your vein. Uh-huh. Um how does uh the oral strips help the absorption? Like you kind of briefly mentioned it, like bypassing your gut and like your gastric like acid and stuff, breaking most things down. Like it would be nice to hear like how you came to okay, the oral route, but not ingesting, but yeah, uh kind of absorbing like most sublingual meds.

SPEAKER_01 13:05

So uh what we were able to do with these is we have a proprietary um formula that we use, and and it varies from strip to strip. So what we use for glutathione might be different than NAD, but it essentially allows the membrane in the mouth to temporarily open up a bit more so that the compounds can get through, and that allows them to be efficient, they close after. Um whereas, like you said, most things like in a pill, you swallow, it goes through what's called force-pass metabolism. Yeah, and that's where a lot of the extreme breakdown is going to happen. So, because we're able to open the mouth and then we encapsulate some of the uh compounds so they can get through even better, those are really the two technologies that have allowed us to get the higher results.

SPEAKER_03 13:42

Okay, so it ends up being more it's closer to like an IV route than an ingestible.

SPEAKER_01 13:50

Essentially, yeah, when you look at advocacy, much uh much stronger compared to the the slower, inefficient orals. Yeah.

SPEAKER_02 13:56

The other thing, dosage-wise, how do you get so much dosage, you know, your the appropriate dosage in such a slip?

SPEAKER_01 14:03

Yeah, such a great question. And um, one of my favorites people are like, Sam, what are we coming out with a with a creatine or a protein powder strip? I go never, guys. We can't fit that much in a strip.

SPEAKER_03 14:12

That would be a big strip.

SPEAKER_01 14:13

Yeah, it'd be like a whole stack of stripes.

SPEAKER_02 14:16

Gummies, you gotta take like these huge gummies to get it.

SPEAKER_03 14:19

And it's still like small doses though, compared to like tons of sugar.

SPEAKER_01 14:22

That's exactly tons of sugar. And then there was a study ran um on it was like over, I think it was two dozen gummies on Amazon, over 50% of them tested as having almost no supplements in there. Yeah, like at that point, you might as well go to fries, get a bag of haribos, and just enjoy those instead because they're not getting vitamins in a lot of your supplement gummies. But um, with these, so initially our our active ingredient capacity, how many supplements or the amount of supplements we could fit inside was around 100 grams or sorry, 100 milligrams. Um, with some recent manufacturing advancements, we're able to get it up closer to 150 now.

SPEAKER_03 14:53

And I know you have a good business idea. Like, well, I'm just gonna make melts without any supplements in them. And I'm gonna charge half the price. Extra lessine scripts, melts.

SPEAKER_02 15:05

Yes, that's funny. But you know, you guys have peptides and stuff that are um, you know, the pro ones, and the peptides I know are like very minuscule amounts already. Yeah, you can pretty much compound into like you know, it would definitely fit into something like this for sure.

SPEAKER_01 15:26

100%. And when we can work in things like micrograms, that's my favorite because the strips are super thin, they dissolve really, I mean, within seconds, they're melted.

SPEAKER_04 15:34

Yeah.

SPEAKER_01 15:34

Um, and with some of the different aminos, they they have a lot easier flavor profiles to work with. So we can do things like orange cream school where you it's like dessert and your supplements, versus um caffeine, for example, is a very, very bitter taste, so much harder to work with. Yeah, um, sometimes it's a fun challenge in the RD lab, but sometimes you're also like, we're going through a lot of iterations and it still tastes gross. But we've been able to get the product to a point where it tastes good. And then we have new products in the works that uh should taste even better.

SPEAKER_02 16:04

Yeah, we've we've done the the supplement thing, and it yeah, it's tough. You're like, I want this stuff in there, balance. We're like, all right, we'll put that in pill form. This will be on the drink form.

SPEAKER_03 16:14

Exactly. Yeah, how long does that taste profile last? Yeah. Like

Melatonin Dosing And Staying Asleep

SPEAKER_03 16:20

you're saying, like even if you come up with a crappy one where the caffeine like leaves a bitter taste in your mouth, like how long would that last? Like three seconds, ten seconds?

SPEAKER_01 16:31

Yeah, good question. So we actually we don't use caffeine in any of our products currently. Perxanthine is the closest that we have to that. Um the so, for example, the brain fuel, which is gonna have more of the you know, bitter nootropics. Um that that currently is a Japanese mint flavor. We mask the the bitter notes pretty good. Some people say they get some of them at the very end for maybe 15-ish seconds. Um, but overall, still a very pleasant experience. It's a strong mint at the start, and that lasts pretty good throughout it. The next uh version of that formula should be even better in masking that entirely.

SPEAKER_02 17:05

Is there any sugar in these strips?

SPEAKER_01 17:07

Zero sugar. So that's what's really nice is there's no sugar, there's no calories, there's no fat. So it's it's guilt-free supplementation um compared to right the creatine gummies where you finish and your hands are coated in sugar.

SPEAKER_03 17:19

Yeah, and 50% of them don't have creatine in it.

SPEAKER_00 17:22

Exactly, exactly.

SPEAKER_02 17:23

Yeah, I I didn't fall for the gummy old gimmick because I was like, you read the bottle and it's like all carbs, and I'm like, all right, this is like can't be I'd rather take a pill that you get zero carbs left. Well, you pretty much break your fast in the morning if you're taking some creatine gummies, if you're if you're doing fasting or anything. Yeah. So makes sense. Yeah.

SPEAKER_01 17:46

Well, it's interesting too. Like when we look at the history of supplements, um, gummies play a pretty interesting role there. Around 100 years ago is when supplement pills became a thing in the US. And that was the norm for quite a while. And then, as we mentioned earlier, pill fatigue, everybody got tired of taking a handful of pills. So they go, okay, what can we do next to make this stuff easier? And that was when powders came out. And then powders became messy, a frother, then you have to clean up your countertops.

SPEAKER_03 18:11

This started around 100 years ago, you're saying? Right.

SPEAKER_01 18:13

Yeah, it was like early 1900s, is when uh pills became a commercial product, early supplement pills. And um, so then it was powders, and then you have to drink this much liquid just to get this much supplement. And then the market goes, okay, well, what can we do that's even easier? It's gonna help people uh be more consistent with their use. And then came the gummies, but then there was all these flaws. And so strips are really the next frontier. We see it as the it's the future of supplements. It's it's a new way to take supplements because you don't have the pill fatigue, right? There's not the powder mess, and um, and you get the faster onset of results and improved bioavailability. So they really tick or check all the boxes of the flaws of prior methods. Um, and they're so much more portable. Like I show people, these are the easy supplements. Um bringing them in your wallet to the gym, whatever it is, you just open the tin, and the strips come inside in these little foils. So you get a month supply per tin.

SPEAKER_03 19:16

And then they're individually packed inside.

SPEAKER_01 19:20

Individually sealed, so super portable. You can bring however many you need. And as my uh famous saying is you peel, peel, peel. The strips inside, you just take it off, pop it onto your tongue, roof of the mouth, and that's it. So in under 60 seconds it dissolves. And can I get one? Yeah, yeah, of course. And this is our NAD. So it's our NATO. NAD is pretty good. It tastes good too.

SPEAKER_02 19:41

Yeah, sure. I just took uh my own trochees I made. That's a methylene blue, yeah, yeah. Methylene blue, oxytocin, and nicotine.

SPEAKER_03 19:53

He originally asked, and our NP responded to where he was trying to get it made from. He's like, Yeah, you don't want to do this because it'll stain your mouth blue. And he's and she was like, Yeah, that he actually doesn't mind that at all.

SPEAKER_00 20:09

That's funny.

SPEAKER_01 20:10

Yeah, it definitely uh when you take methylene blue, people know you've taken methylene blue for sure. Yep.

SPEAKER_02 20:16

Yeah, I took like four or five of these tins to when I went to St. Martin, like yeah, I just put in my backpack. I took as a carry-on. Oh, that's good, yeah.

SPEAKER_01 20:26

Yeah, yeah. It's like property. Vanity is our number one seller we've sold. Yeah, I mean, hundreds of thousands of things.

SPEAKER_02 20:32

It tastes good and you feel it like immediately almost.

SPEAKER_01 20:34

Yeah, yeah. And no poke. Um, and you're like when you're traveling, right? Typically it would be you know, a bag of pills, a bag of powder. TSA is like, what are you bringing through here? So much easier. Um, and you you never have the hold up in the airport.

SPEAKER_03 20:46

No, it doesn't matter. TSA is gonna give me crap from I'm Iranian, I don't shave my beard, so uh I'll I'll I'll I'll get screened either way. Your name's not Abdul, so thank god or Muhammad. I have some positives that's too funny.

SPEAKER_01 21:04

That that is really good.

SPEAKER_02 21:06

Yeah, the NAD strips.

SPEAKER_03 21:07

I would take that as a mint.

SPEAKER_01 21:08

I know some people eat them like candy, I'm like, God. No, I know that's that's the thing. I'm like, ah, that's really good.

SPEAKER_03 21:14

I know we want to live to 150, but like I'm living to 225 today.

SPEAKER_01 21:20

You're gonna beat Brad Johnson.

SPEAKER_02 21:22

Well, I I got the NAD nasal spray, and then I led him onto it, and he he did like what four sprays once. Uh it was like six to eight sprays.

SPEAKER_03 21:31

I got up like hungover, and I was like, oh, this stuff makes real good. It's great hangover juice, and I was like dragging, so I just kept spraying. Oh man.

SPEAKER_00 21:42

And then flat NED.

SPEAKER_03 21:44

No, I was just like things started tasting weird. I didn't put two and two together, but I was blowing out my like nasal receptors because um it's actually like almost a positive side effect. In a different route because I blew out certain uh taste

Glutathione Timing And PK Data

SPEAKER_03 22:05

and sense uh uh nasal receptors, but it was all for sweets. So I couldn't taste sugar.

SPEAKER_00 22:12

Okay, that's not too bad, I guess.

SPEAKER_03 22:14

I could I I taste sour, salt, all that stuff, but I couldn't taste sweet because I had like uh it was some type of protein bar. Uh-huh. And I swear it tasted like just biting into like a stack of hay. I was just like, what the hell is this? Like I actually enjoyed this protein bar. And I was just like, this is this is god awful. Like that's so funny. Legit took like a good six months to build back up. I it's quite a while. Yeah, I went on a taste test for somebody's event. Oh no, it was our supplements. When Matt came by, was like, taste these. I'm like, they all kind of taste the same to me. I don't think I'm the right person for this. Yeah, uh, this one. But he's like, Well, which one do you like the best?

SPEAKER_02 23:04

I'm like, none.

SPEAKER_01 23:06

That's too funny.

SPEAKER_02 23:08

So, what are people taking the NAD strips for?

SPEAKER_01 23:11

Yeah, great question. So, NAD, a lot of people take primarily for longevity. Um, it's a great staple for healthy aging protocols and then energy and mental clarity too.

SPEAKER_02 23:20

Yeah. And how about like, you know, a lot of people talk about how NAD doesn't get into cells and like why not NMN? Um, or what's the other one? N R. N N R, yeah.

SPEAKER_01 23:33

So we actually do have an NR script coming out soon.

SPEAKER_02 23:35

Oh, yeah.

SPEAKER_01 23:36

Um, NAD typically provides more of an immediate hit, and so people like the the fact, right, like like you said, that they notice it first day immediately, the brain fog can go away, that they get the energy boost. Um, and then some some of NAD in the bloodstream does break down and then get recycled and turn into the precursors that then get turned into intercellular NAD.

SPEAKER_02 23:53

Could you put both NAD and NR in the same strip, or is that so because of dosage, it would be very challenging right now to get um effective levels in each one.

SPEAKER_01 24:03

Yeah. But the idea is good. And what's interesting with NR actually, there's some research because when you look at NAD, there's um an enzyme called CD38 that just eats up NAD as we get older. Yeah. It eats it faster and faster and faster. CD38. CD38.

SPEAKER_03 24:17

And uh the analogy I like to use it's like the jose of our body's enzymes.

SPEAKER_01 24:23

Uh it's kind of like a bathtub if you think about like an open drain and then water is flowing. If CD38 just keeps consuming, the water is just gonna keep going down the drain.

SPEAKER_03 24:32

It's like yeah, yeah, it's it's it's like the jose of supplement. Like we kind of want to keep going with our podcast, and he keeps holding up time. Five minutes left, guys, ten minutes left.

SPEAKER_00 24:45

That's too funny. Um I can't see behind me. What's that? Is there a sign going up for 10 minutes?

SPEAKER_03 24:54

Not yet. In about two minutes. Okay, it's gonna be like 58 minutes left, guys. He's gonna walk around like Vanna White holding up the sign.

SPEAKER_00 25:03

I love it.

SPEAKER_01 25:04

Um, but ideally with NAD, if we can inhibit CD38 and then restore NAD levels, that's what's gonna give more of the optimal long-term benefits. And so NR is being studied to help inhibit CD38 and restore the NAD levels. So that's a product that we're really, really excited about.

SPEAKER_02 25:21

Yeah, because I feel NR much more, you know, NMN, I think like you take it for longevity, you don't feel the difference, but like NAD, like these strips or the nasals spray, I think I feel it. And then NR, like taking it as an oral supplement, I totally feel it. Like, especially like the you know, the daily greens I would I take on and off that has NR, and I can totally feel the energy from that.

SPEAKER_01 25:49

Yeah. Well, and like with NAD, I something that's really um important. I was just actually having a conversation yesterday morning about it, is understanding the timeline there. Because so many people, certain supplements like our brain fuel and our sleep are formulated to kick in the first time, uh the first day when you take them. Um but things like glutathione and NAD, since they decline as we age or decline when we drink, um Why'd you look at me? The hangover story. Um so yeah, those are are great actually post-day to help with the hangover. But when trying to build those levels back up over time, it can take sometimes a couple months or sorry, a couple weeks to a couple months for different people, um especially as we get close to the 50 mark because our NAD starts declining around 25. By 50, it's around half of what it used to be. So um results can vary per person, but I would definitely say give it a couple months if you're gonna try it and then sort of evaluate next steps from there.

SPEAKER_03 26:38

With the NAD?

SPEAKER_01 26:39

With the NAD, and also probably the glutathione too.

SPEAKER_02 26:42

And that one's gonna be more of the uh the skin benefits and also detox at the and aside from the supplement, you know, the supplement stuff, talking about the peptide side of things. What do you guys carry in the peptide uh world? But I thought it as long as it's not injectable, like you don't need to so the rest is supplemental, yeah.

SPEAKER_01 27:04

Based off some recent guidance from legal counsel, they say put the RU on there to be safe because so it's different when things are injected, that tends to put it in more of a farce uh pharmaceutical uh class. But because they're still pending FDA approval, getting close. I mean, the FDA committee this summer, you know, just had a strong push, especially for peptides like BPC, but they're still uh kind of pending. So for right now, they're they're uh researchers only. But um yeah, so our proline has different aminos. Um I mean the most popular peptides right now are the glow stack or the wolverine stack or the wolverine stacks. So uh BPC 157, TB500, GHKC. That's gonna help with connective, or that's it's being studied for connective tissue repair, skin and hair, gut health, reduce inflammation. Yeah. Um, then there's things like CJC, 1295, and epimeralin. And those are growth hormones who created obviously help with everything from or being studied to help with things like sleep and muscle development, um, famous peptides, you know, GLP1s, insulin, retta, elolie is obviously doing a very good thing.

SPEAKER_02 28:02

I was gonna ask you, how about the GLP ones? What are you doing?

SPEAKER_01 28:05

Yeah, so uh, in a delivery delivery format. It's actually in the pipeline and uh launching soon, which we're very, very excited about because what I think is really powerful about GLPs um and these weight loss peptides, is it's getting to the point where it's making obesity a choice. And in the past, right, obviously people's um health journeys are very, very complex, and there can be a lot of reasons why weight can be put on or can't be lost as easily. And what these peptides do, especially as we go from something like GLP to more of a redotrutide, is it makes the process so much easier. Um, now with that, too, one of the issues that I see people making

Sublingual Tech Dosage And Taste

SPEAKER_01 28:45

with those on the provider side is dosing too high. And then you get kind of that skeleton look, right? That we see in some of the people in Hollywood and other places. Um, so you want to start low typically, titrate up is what a lot of studies are showing to be uh to produce the best results.

SPEAKER_03 28:57

In our practice.

SPEAKER_01 28:58

Okay, awesome. Um, so GLP, and then we have an extra thing on that side, an extra product on that side that's um in the works to a novel peptide that our team has created uh that should be very, very effective. So we're pretty excited about increasing the access because it comes down to again, people don't want to poke, but yeah, people want to live healthier lives, and so we're gonna help uh do you guys offer CJC? Yeah, so we do have CJC in IP um in one strip. And you take that twice a day.

SPEAKER_02 29:23

No, you do our schedule. Okay.

SPEAKER_01 29:26

So those right now, uh, some people take in a five days on, two days off protocol, some people take daily. It just depends on how aggressive they're trying to be and increasing.

SPEAKER_02 29:32

It's once a day.

SPEAKER_01 29:33

Yeah, typically once a day uh before bed is what a lot of people do for that.

SPEAKER_02 29:37

Okay. Yeah, it's you know, for like most maintenance, it's once a day. For like when you're trying weight loss, you do it like before you go to bed. Yeah, at times where your growth hormone is gonna spike, you do it like before you go to bed, you wake up. And some people do it three times a day before they work out or something. You know, it's dependent on like your lifestyles and your and goals. Yeah.

SPEAKER_01 30:01

Yeah, a lot of the protocols are definitely customizable for sure. Um, so I it's always best just for people to figure out what works best for them there.

SPEAKER_02 30:08

What what drives me nuts is I know like these are all research use peptides, and but like a lot of people, you know, once they they become influencers, they discuss this, and John Jay actually had the lady on there, and she's an influencer, and it just drives me nuts when they're like there's no human data, and they just keep on pushing that point and FDA clearance, and I'm like, these are being pretty widely used, and it's not anecdotal evidence when there's millions of people get an improvement, but that's still anecdotal if it's not set up set up correctly, but yeah, um, whether it's placebo or not. But like when you when you see the effects of these peptides on people, you can't kind of deny what's actually happening when you know, and it it has animal data, it doesn't have the human data, and we're probably never gonna see that human data because they can't patent it to make it into a drug.

SPEAKER_01 31:10

So there actually is some happening. Um, but I'll kind of share a quick story on the history of the peptide. So a lot of these peptides were first identified by a guy named uh Dr. Robert Cavinson, he was a Soviet scientist. Yep.

SPEAKER_03 31:23

And he's that the guy that patented BPC.

SPEAKER_02 31:27

Uh epitalon.

SPEAKER_01 31:28

Yeah, yeah, he helped with a lot of the discovery. I don't recall if he had the BPC now.

SPEAKER_02 31:32

It wasn't BPC, more towards epithalon, I think. That's right.

SPEAKER_01 31:36

Okay, go ahead. Um, and so he he was helping develop these and um find these for their their cosmonauts and their soldiers.

SPEAKER_04 31:44

Yep.

SPEAKER_01 31:44

And then when the Soviet fell apart, a lot of the science kind of was suspended. No one was continuing the research and some of the stuff got lost, and now it's making its way west. Um and Andrew Huberman, the uh big scientist and researcher over at Stanford, he's helping. He's brought on some really, really great uh researchers and and physicians in the space to help educate on what these peptides are, um, where they're at in the the clinical study process. And then I know there is a big study that is, I believe, in progress uh for BPC. So should have some new data there.

SPEAKER_02 32:16

Yeah, BPC is the one that yeah, he hits on his new new book too that like they're working on the studies to kind of prove how and some of them have already been studied, like tesmoralin. Tesamoralin's known to actually work, and and when you got compounds that are very similar and things, other things that have already proven like how could you discount like how effective some of this no, I'm not talking about effective, like something like BPC, I don't think it's been thoroughly studied for like risk factors rather than benefits.

SPEAKER_03 32:53

Um so like like in a large, like even phase three trial, where most medicines are of I mean all medicines are put out before they go to phase four. Phase three, they give it to a bunch of humans and see like okay, they're they have this downside effect. Yeah, so that that's uh that's the thing that's not there where it won't push it to like I mean it's already a mainstream use, like from what I see. Yeah, but people are like, uh, okay, well, I'll I'll be the guinea pig and I'll try it out because it I feel like it's helping me out.

SPEAKER_01 33:30

Yeah, well, as you were talking about the patents earlier, like it's really hard. Pharma um definitely, you know, they make some incredible stuff, but they also are in the business of creating novel compounds that they can patent, and that's that's our business model. And so with something like BPC where it's naturally found in our body and they can't patent it, there's not an incentive for them to lead those studies, and so then it falls on companies like us or other um private individu or private uh parties to to fund that research and pool together anecdotal data and see um really at a high level and at a significant volume. Like, what are we seeing? I mean, I've spoken with some of the biggest players in the peptide industry in the US, and they say that across the board of like the most commonly used peptides, um almost no safety complaints. Typically, there are when there's a health issue from them, it's because the source was bad, uh, they were reconstituted incorrectly, and then they were taken incorrectly.

SPEAKER_04 34:23

Yeah.

SPEAKER_01 34:23

So it's kind of uh not that they're the perfect diagree, more researchers always need to be sure. But a lot of the stuff is user error, which is kind of unfortunate because then with social media, someone goes, oh, BPC costex race.

SPEAKER_03 34:34

I'm like, well,

NAD For Longevity CD38 And NR

SPEAKER_03 34:35

even like CJC made me have this type of reaction, but exactly like there's no studies on the purity or the actual amount, like what's in what they were injecting.

SPEAKER_01 34:46

Yeah, and that's why it's so important to get COAs, which stands for uh certificate of analysis, and that's gonna show purity and making sure there's no mold, heavy metals, et cetera, or at least you know under the safe levels, which is very, very small amounts. Um, and that's something where if you're getting it from a supplier, you want to be able to verify that because some of the some of the players in the space are putting at COAs that are forged that don't have accurate information. And so there's a couple um well-known labs that you want to look out for uh on the testing. Like, for example, on our supplement side, we test primarily with Eurofins and NSF, which are some of the most well-known and trusted global labs. Um, so just always something good to look out. If it's a lab you've never heard of or seems kind of sketchy, probably want to take it up.

SPEAKER_03 35:27

When we get peptides to patients who it's trusted uh compound pharmacies that do testing, repeat testing, like regular testing. You gotta track lot numbers 100%. And like, you know, you you might get a bad batch, but it's like making sure that that ends there rather than like just keep distributing garbage to people.

SPEAKER_01 35:49

Yeah, I think that's a great approach. Do you guys have um a favorite application of peptides that you've uh you found in or with uh folks you know or I personally myself I that's I just like the terzepitide.

SPEAKER_03 36:04

It's um for my for me, for what I want, I just want to shed about 10, 15 pounds and not have that um just like a hunger drive. Like I'm going through my day and I got this urge to eat, and even subconsciously, it overtakes a lot of things. I notice it first when I was studying for my boards in med school that because I was like, okay, what what's going well, what's not, and I could see it in the results from my the practice exams I took. And those those are just hard numbers, and it's this very similar test each day. I'm like, um doing better in the morning than I am at night. Little things like if I get one wrong, I tend to get three or four wrong in a row. So that taught me to just take a step back if I have difficulty with one question, make sure that doesn't like snowball into the next question. And the last thing I noticed was approaching lunchtime, my scores started to decline. And then after lunch, my score, if I ate, my scores just fucking tanked. Like they went down. They went, it was garbage because my body was using uh what I think is my body's using all of its energy to digest that food that I just injected. Uh-huh. So my mind doesn't have that same source of NAD naturally. Like, cause so then when I went into the exam, I just ate like something like a quarter to half protein bar or like a quarter to half sandwich between each hour block. So I wasn't interested just eating a whole meal at noon and then like doing well and then just tanking. And that like even leading up to the exam doing practice exams, I found out that that worked best for me. That's how I maintained like a high performance on each block because like eight hours of testing in one hour blocks. And that that really like, I was just like, oh, this is this is what I need to do. So I just took I wouldn't say minimum amounts, but like I I took my regular breaks because they're like you have this amount of breaks, this amount of lunch, you can use it in this amount. So I was like, okay, just go eat half a protein bar, go eat a quarter sandwich, and and just like I consumed the same amount I would, but like I think that really helped out my performance because it my energy level was like optimum throughout the day. Yeah, but I don't do that every day because I'll go operate for like not during surgery six hours. Yeah, yeah. But the this this you could do this sterily, yeah. Popping a tab.

SPEAKER_02 39:02

We we use a lot of stuff for repair and recovery. So um all our patients get the Wolverine stack oral form um of Wolverine stack. So yeah, that's what we're mainly using. But you know, I I take Reta, I take CJC of Pomoran. Um, and you know, a lot of it we discussed a lot a couple weeks ago too about needle fatigue. You get, you know, you're like when you're off on the weekends, you're like, oh, thank God, yeah. You know, so um that's nice, but it it's good to have some of these things to, you know, and that that's where the oral, you're always wondering whether the oral is gonna function as well with the Wolverine stack as injectable because the injectable is gonna definitely be more effective

Peptides Safety COAs And Real World Use

SPEAKER_02 39:55

when you do have the well, when you had surgery, it's trauma and injuries that need repair, I think is more effective where I I know you can probably formulate the oral form to where it can be effective. It's gonna be effective as an anti-inflammatory and help recover the gut, but is it gonna be as efficient at getting to those injured sites and helping them heal?

SPEAKER_01 40:19

Yeah, that's a great question. Um, and I'll share like a personal story and then a couple other stories of testimony that we've got. So I think it was around three years ago. I was in the gym, I was doing an overhead dumbbell press. And you know, when you're at the end of a set and you think you can get another rep or two out, yeah, but you really can't.

SPEAKER_02 40:35

Yeah.

SPEAKER_01 40:35

So that's what happened. I was going, going, going, and shoulder dislocated. I dropped the dumbbell on myself, shoulder popped back in place, and for two years the mobility was horrible. I mean, it would crack, hurt, like I couldn't lift the same. My right arm and I was looking like Popeye, and then you know, and um, within around a week or two of taking the the glow strips that we have, yeah, pain free and shoulders been been great since.

SPEAKER_03 40:59

Um, there was a guy recently who that's a great exercise that a lot of people I know I've hurt myself on over the press.

SPEAKER_01 41:06

It's fun, but it hurts. Yeah, yeah. And and I feel like when I hear about gym injuries, everyone's like, oh, my shoulder hurts. Yeah. Um definitely like with uh tennis double, for example. There was a guy uh met through uh or met online recently uh through LinkedIn. He was talking about taking the Wolverine injections, and he actually said he's like, I'm not really getting the benefits. I don't know where he was sourcing his stuff from. Um, but I messaged him, I go, You have to try our product. Like I promise it's it's gonna help. And he messaged me uh it was a couple days ago. He's been on the stuff for probably a week or two now. And he goes, Sam, like wildly. I didn't think these were gonna work, but I'm feeling the best I have in once. Um, and so in some cases, people notice benefits actually better than injections. But I mean, injections, if you look at a bioavailability comparison chart, because it's a needle going directly in, yeah, you're gonna get, you know, typically maybe like 98, 99% bioavailability. Whereas the strips, right? We're at up to 94. Yeah.

SPEAKER_03 41:58

Um that's really good.

SPEAKER_01 42:00

Yeah, it's it was a great breakthrough because uh like pill, I don't know what the pills can. BPC works orally, yeah. GP500 and some of those other peptides are are definitely um more difficult. But yeah, we've had people use them for for back pain, uh, gut health, yeah, hamstrings, you name it, and the strips they get to the point where they need to be and really provide assistance.

SPEAKER_02 42:19

Yeah, because it's the right dosage, like it should be effective. And like a lot of the other differences are even like, you know, I don't go to the gym that often, but I do hit it hard when I do. And it's you know, you do those leg days, and you're like, I'm not gonna be able to work for uh walk for three, four days, uh huh. And you're just up and around the next day. I'm like, maybe the next day's gonna get worse, and it doesn't. And like that's that's where you know it's it's not anecdotal. It's like at my age, like like 47 now. Like in my 30s, I used to be freaking like, you know, after three, four days I used to still be in pain, and now it's like recovering much quicker than that. So it's definitely a difference from before.

SPEAKER_03 43:04

Recovery seems uh faster than I would think. It's not like I'm lifting as heavy as I was when I was younger, sure. But yeah, on on stuff like BBC, again anecdotal because it's my story about it, but um it seems like recovery is a lot faster. You don't have like just all worked out legs, so both my legs are like just noodles. Do you guys have a supplement or peptide that that can cure a pesky um like podcast producer?

SPEAKER_00 43:42

That one uh we'll have to add to our R D. We won't add that one just yet.

SPEAKER_01 43:50

Um but actually one other funny story with the the glow strips, and there's one other one. So we have strips called passion strips, they're uh intimacy support. The main intimacy support. But they work for men and women compared to someone like Viagra, which is just geared towards the men. Um, and there was a guy who he's been a user now for he's been taking notes for probably four or five months. Um, and he took the the glow strips after his workout and then the passion strips uh with his wife later, and he'd text me all caps. Those are amazing.

SPEAKER_00 44:23

I was like, I'm so happy you're enjoying them.

SPEAKER_02 44:26

But sometimes uh people share too much, like, oh guys, just a thumbs up or thumbs down, but those are nice because uh like what's in that so it has pt 141 oxytocin. Are you guys thinking about adding like uh Viagra or cellenthyll or one of those in there?

SPEAKER_01 44:43

So we use a compound called uh amino phenolpyral, it's a similar thing, so it supports the the male performance. Um and then the ladies, well, like both partners get um increased arousal from the PT141, is uh really what that's for. Um, and then in our initial formula, we have B3, which gives a bit of that flush feeling and helps with the healthy circulation. Um, but yeah, couples always like that one, uh, especially you know when uh couples have kids and then getting to things like menopause or postmenopause and some of those challenges can be uh

GLP Plans Recovery Stories And What’s Next

SPEAKER_01 45:15

more present. PT141 can be a great pest.

SPEAKER_02 45:17

Yeah, a lot of a lot of the guys I know they always ask me for the trimex. With I think that amino thylene as part of the trimex. Um increases the blood flow.

SPEAKER_01 45:30

Yeah, yeah. All throughout the body, uh more targeted in certain areas. Yeah um veins, I'm guessing something like that. Uh yeah, I mean lots of different products, but we tell people like we have essentially a strip for basically everything. If we don't have it yet, it's probably in the pipeline.

SPEAKER_00 45:48

Okay.

SPEAKER_01 45:49

Um, for example, we have a nicotine alternative strip that's coming out soon. We're really excited about that. So if um actually kind of looking at nicotine, obviously, zins are really, really popular. Vaping is still huge here and uh overseas. And when looking at vaping, a lot of the oxidative stress that is put on the lungs occurs when the the juice, for lack of better terms, is burned and then is turned into the aerosol. And so that's one of the things I'm excited about with that strip is you don't have to burn it. You you get the a similar nicotine or nicotine like that's the biggest problem.

SPEAKER_03 46:20

Like the thing just like combustible anything is bad for your lungs. It doesn't matter.

SPEAKER_02 46:27

And even the zinc, the n well, who knows what's in there on top of the caffeine and the nicotine, and even the nicotine, you know, like if I'm doing it, I put it in for a second and I spit it out to get because they're usually like what the even their mini dose is like six milligrams, and I try to get maybe one milligram of nicotine. Yeah, it could be quite a bit, yeah.

SPEAKER_01 46:49

And then you have to worry about spitting out. So actually, these you can take on planes on like a vapor or something if you need.

SPEAKER_03 46:54

I just like to double pack. We used to call we used to call it the double deckers with the skull. You just full pack your upper lip and your lower lip, and then just try not to throw up.

SPEAKER_00 47:05

Now you can put a melt on your tongue, both cheeks, and the roof of the mouth. Just put a hole I don't recommend that the thing right in.

SPEAKER_02 47:14

So it's a nicotine alternative. That's interesting.

SPEAKER_03 47:16

So lower toxicity profile. So it's from what's the compound in there? Sorry.

SPEAKER_01 47:23

Um, it's it's uh synthetic nicotine or nicotine alternative, so it's not derived from um tobacco. Um, it's a fairly new compound, uh, but it it should be a hit. So we're excited. That one's gonna be a strong peppermint flavor.

SPEAKER_03 47:36

So you have to get approval from like same types of boards as a nicotine product.

SPEAKER_01 47:41

Good question. So when the compounds aren't derived from um tobacco products or they're not nicotine themselves, um the current standing is is no. And so it's helpful again in increasing access and having people try the stuff to see what works best for them.

SPEAKER_02 47:57

Because because there's the yeah, I see the Instagram, what's it? P there it's not it's the new one that's got three different like non-nicotine stuff. It's a pre-workout ultra or vello or it's like PMR or something. Yeah, it's a newer one that's got three different things, and I think it's got parasanthine, I forget what else it had in it, but like alpha. It's supposed to be like a yeah, something like that. It's supposed to be like a pre-workout, like Zen.

SPEAKER_03 48:28

I mean, it's it just goes to show you kind of like the even the nicotine market shifting. Like you saw vapes starting to catch a lot of j just going by what's on the counter in the back of a gas station. It's like vapes were starting to take over, and now it's like majority is like Zen and Zin-like products, yeah, and uh cigarettes are slowly diminishing, they're maintaining their like 25 to 40 percent of the counter space. But yeah, any healthy alternative to uh whatever's out there would be really good.

SPEAKER_01 49:08

Yeah, 100%.

SPEAKER_03 49:10

All right, so where where can people find more about melts and order the system?

SPEAKER_02 49:15

And when are you gonna be on Amazon? Oh, Amazon's shop. Um I can open up an Amazon shop for you guys.

SPEAKER_00 49:23

Yeah, if that's what it takes.

Where To Buy Amazon Timeline

SPEAKER_01 49:25

Yeah, we actually we went through like months and months of testing with NSF, thousands of dollars. Passed all the tests and easy like that. So that was an issue, but um because we're updating some of the formulas, it means a whole new batch of testing, which is like months. So my guess is probably 2027. Um and then for finding products, everything's available on getmelts.com. So that is your go-to place for our supplement strips and then a pro line as well. Yeah, um, we ship basically everything same days, so I tell people we we're like Amazon Prime, we get it out quick, just uh direct from the source.

SPEAKER_02 49:59

We just need an affiliate link on our website.

SPEAKER_01 50:01

Yeah, we'll get you guys set up there.

SPEAKER_02 50:03

Awesome, easy peasy.

SPEAKER_03 50:05

All right, thanks for stopping by.

SPEAKER_01 50:07

Of course, thank you for having me on the screen with a new bit of